Pharmaceutical Melting Point Apparatus equipment is designed to quickly measure the Melting range and point of certain substances. Some samples can be tested simultaneously and safely in the analyzer of the Bench-Top Melting point. Purchasing considerations for Pharmaceutical Laboratory Melting Point Analyzer includes the temperature range of instruments, user interfaces, and test heating times.
Melting point apparatus is a laboratory device used to determine the melting point of an element with precision and large accuracy. The temperature in which the state of a substance changes from solid to the liquid is said to be the melting point. Melting a substance is generally obtained by heating it. This is one of the most important and basic parameters to know about the nature of a substance, determine its purity, and characterize organic and inorganic compounds. Pure elements generally have a sharp and high melting point, while an impure and contaminated element has a low melting point and takes a relatively longer time to melt completely. The higher melting point than a substance implies that there is a high magnitude intermolte power. Most melting point apparatus can display the initial and final theft points of an element. In addition, some of them are equipped with a mechanism that can record and display the melting point curve and determine the average value of the melting point.
Working Principle of Melting Point
The melting point apparatus usually works on the principle of reflectance and light transmission falls and passes the sample. Changes in light transmission are easily visible; Therefore, the melting point apparatus work is not too complicated. The process of smelting a substance can be categorized into five stages, namely, moisturizing, sintering, collapsing, meniscus, and clear points. The most point is the initial stage of melting elements. In the collapse stage, the substance is largely solid and contains a little liquid material. At the point of the meniscus, most of the samples will melt but still contain several solid particles. The substance is said to be fully melted after reaching a clear or gradual point. The intensity of passing through the sample varies throughout the stage of the melting process of substances and is easily noticed.
Working of Melting Point Apparatus
The standard method used by the melting point device to determine the temperature at which melting object is the capillary technique. To determine the melting point from the sample with the help of the melting point apparatus, the sample is placed into several capillary tubes. The capillary tube is then placed in the heater block. Samples are analyzed individually and the average measurement is obtained to determine the right melting point of the substance. The first step of this technique is sample preparation. This substance is placed in a vacuum device for one day to ensure that the sample does not contain moisture and dried correctly. Dry samples are then destroyed into fine powder. This is done because granules of rough and non-homogeneous samples will receive an uneven amount of heat, and the device will not be able to provide accurate measurements. The compact layer is around 2-4 mm at the height of the soil sample correctly then placed into three or more thin glass capillary tubes. The powder sample placed in the capillary tube must be tightly packed. This can be done by tapping the tube gently to a rigid surface. The capillary tube is then placed in the heating block from the melting point apparatus that provides the temperature needed to melt the sample. The temperature block heating can vary according to sample density. The temperature in which the sample experienced five stages of smelting was observed and recorded. During the process, some samples were not disbursed, but, but, they underwent sublimation and converted to gas form directly. This must be recorded manually. The internal mechanism of the device records the temperature in which the sample starts to melt and the temperature when the substance is fully merged. This temperature interval is said to melt the melting range of these substances.
Use of Melting Point Apparatus
1. Melting point apparatus is usually used in the research and development domains to study certain solid structures and characteristics.
2. The Melting Point apparatus tells the purity of a substance, which is why it is clearly used by the quality control department of various industries.
3. It is used by the pharmaceutical and medical industry for drug testing.
4. Perfume industries utilize melting apparatus to produce aromas have different fragrances.
Safety steps when using melting point apparatus
1. The device must be operated in just in the limited temperature range specified.
2. Do not move or carry a machine when used and connected to inventory.
3. Take advantage of Weakable and safety tools such as protective gloves, safety glasses, container clamps, etc., to handle heat samples.
4. Store devices and samples of combustible and flammable objects to prevent fire and accidental hazards.
Advantages of melting point apparatus
1. Melting point apparatus provides fast and accurate results.
2. It’s compact and portable.
3. The accuracy and precision level of melting point apparatus is significantly higher than the traditional method of calculating the melting point of a substance.
4. It is suitable for calculating the melting point of pure and contaminated substances.
Disadvantages of melting point apparatus
1. The melting apparatus can only be used to determine the melting point of solid substances.
2. This device is specifically designed to observe sample substance conversions from solid forms into liquid. If the sample substance experiences sublimation or deposition, it is necessary to be recorded manually.
Other Posts Related with
Cleaning SOPs for Melting Point Apparatus
Operational SOPs for Melting Point Apparatus
Calibration SOPs for Melting Point Apparatus
Installation Qualification of Melting Point Apparatus
Operational Qualification of Melting Point Apparatus
Performance Qualification of Melting Point Apparatus