The pH is a measure of alkalinity& an aqueous solution’s acidity. This is dependent on the comparative number of hydrogen ions (H+) or hydroxyl ions (OH-) in the solution. Higher relative number of hydrogen ions; conversely, alkaline solutions have a higher relative number of OH- ions in acidic solution.
In water, the absorption of H+ and OH‑ may vary over 15 orders of magnitude. The Henderson–Hasselbalch equation allows pH to be derived from the quantity of H+ using pKa, the negative log of the acid dissociation constant, in biological and chemical systems. Most of the Pharmaceuticalsas part of their process measure pH to assure product quality.
A pH meter is a scientific instrument that measures the hydrogen ion activity in water-based solutions, indicating its acidity or alkalinity expressed as
pH = – log [H+]
In the Pharma industry, pH is basically used to regulate the physical and chemical reactions needed to produce food and prevent pathogen growth. This is exemplified while producing milk and alcohol drinks because it involves fermentation.
Useful yeast and chemically mold modify input materials work optimally at certain pH. Furthermore, the pH value must be monitored to inhibit the growth of pathogenic microorganisms that can cause food decay or have a negative impact on the taste and quality of the final product. then you can accurate pH measurement equipment can compliance with food security regulations and ensure product Quality.
Working Principle of ph Meter
PH meters are used to determine the acidity or alkalinity of the solution. PH is a concentration of hydrogen ions in solution. Contains solutions
More H +.
PH meters are used to determine pH of various solutions in pharmaceuticals. This is a more accurate method than a pH strip. The pH probe that passes the electrical signal to a pH meter and a pH meter displays the pH value of the solution.
Iron remains sour while the solution containing more oh-ion remains alkaline. The value of pH solution ranges from 1 to 14.
The overall working principle of pH sensors and pH meters depend on ion exchange from a sample solution to the inner solution (pH 7 buffer)
glass electrode through glass membranes. Glass membrane porosity decreases with sustainable use that reduces
Cleaning SOPs for PH Meter
Operational SOPs for PH Meter
Calibration SOPs for PH Meter
Installation Qualification of PH Meter
Operational Qualification of PH Meter
Performance Qualification of PH Meter