SOPs

Standard Operating Procedures (SOPs) provides end-users with clear instructions on how to work and develop enough to ensure that all end-users can perform their tasks in a consistent and consistent manner. Many processes can be difficult, and it is important to have a balance between too few and too many points. If there are too few points, the end-user will follow their path. On the other hand, too much information and too much detail increase the risk that the end-user will struggle to understand and perform everyday steps, resulting in errors and omissions.

Sops are of different types like Quality Control SOPs, General SOPs, Production SOps, R&D, Regulatory and Validation SOPs etc

Jan42022 by KBS.No Comments

Calibration SOPs for UV Spectrophotometer

SOPs

Calibration is one of the most frequently used techniques in pharmaceutical analysis. This involves measuring the amount of ultraviolet radiation or seen absorbed by a substance in the solution. The calibration instrument measures the ratio, or function ratio, from the intensity of two light beams in Qualitative UV analysis, organic compounds can be identified using spectrophotometers, if there are recorded data available, and quantitative spectrophotometric analysis is used to ensure the quantity of molecular species that absorb radiation. Calibration of spectrophotometric techniques are simple, fast, quite specific and applies to small quantities of compounds. Fundamental law that regulates calibration spectrophotometrically analysis PURPOSE: To describe the Calibration procedure for...

Jan42022 by KBS.No Comments

Operational SOPs for UV/VIS Spectrophotometer

SOPs

UV/VIS Spectrophotometer Operational SOPs method is used to measure the pharmaceutical and non-pharmaceutical compounds that have detectable peaks in the UV-Vis region PURPOSE: To describes the operating procedure for operation of UV/VIS Spectrophotometer. SCOPE: This SOP gives detailed outline for the operation of UV/VIS Spectrophotometer and will cover operating procedure of equipment. RESPONSIBILITY: QC Analyst is responsible for operation of equipment and preparing standard operating procedure. It is the responsibility of QC Manager to assist and ensure Operating Procedure’s as per SOP and to make certain that this SOP is followed in its entirety, reviewed regularly and revised as necessary. REFERENCE: In-House Specifications MATE...

Jan42022 by KBS.No Comments

HPLC Waters Pda With Quartnary Pump – SOPs

SOPs

This SOP HPLC WATERS PDA WITH QUARTNARY PUMP most important who gives a detailed outline for the operation of HPLC 1 Waters PDA With Quartnary Pump and will cover the operating procedure, calibration and cleaning of equipment. PURPOSE: To describes the operating procedure for operation of HPLC 1 Waters PDA With Quartnary Pump. SCOPE: This SOP gives detailed outline for the operation of HPLC 1 Waters PDA With Quartnary Pump and will cover operating procedure, calibration and cleaning of equipment. RESPONSIBILITY: QC Analyst is responsible for the operation of equipment and preparing standard operating procedures. It is the responsibility of QC Manager to assist and ensure Operating Procedure as per SOP and to make certain that this SOP is ...

Jan32022 by KBS.1 Comment

Cleaning SOPs for UV Spectrophotometer

SOPs, Quality Control

In this article detail is given of Cleaning SOPs for UV Spectrophotometer, how to clean UV Spectrophotometer in Quality control Laboratory of Pharmaceuticals. OBJECTIVE To lay down the procedure for cleaning of UV/VIS Spectrophotometer. SCOPE: This shall be applicable to the UV/VIS Spectrophotometer installed in Quality Control instrument Laboratory. RESPONSIBILITY: Technical Assistant/ Helper. C Analyst. ACCOUNTABILITY: Manager-Quality Control. MATERIAL AND EQUIPMENT: UV/VIS Spectrophotometer. Clean dry cloth. Tissue paper. Dilute soap solution. Purified water. PROCEDURE: Ensure that the power supply to the instrument is switched OFF before cleaning. After completion of the testing, remove cuve...

Jan32022 by KBS.No Comments

Washing Of HPLC Column SOP

SOPs

Here is the WASHING OF HPLC COLUMN, it is very important in the laboratory, if not done can correctly affect the health of your column. Cleaning your HPLC column may be simple, but it is very important for efficiency, lifetime, and productivity instruments. The ineffective HPLC column can affect your analysis, resulting in inaccurate results, which means more time spent on the same project. The following SOP focuses only on how to clean your HPLC column through reverse flushing. It may be time to water your HPLC column when you see high back pressure, low efficiency, split peak, or the most common problem, the particulate buildup in the head of the column. Now we move to Washing Of HPLC Column SOP Objective: This method is applicable for washing of HPLC column. Sco...

Jan32022 by KBS.1 Comment

Operational SOPs for HPLC (High Performance Liquid Chromatography)

SOPs

In this post, we will study Operational SOPs for HPLC (High Performance Liquid Chromatography). All the related outline, scope, responsiblity and procedure you will study here. 1. PURPOSE To outline work instruction for “HPLC” in Quality Control Department. 2. SCOPE To separation of different material in solution in Quality Control Department. 3. RESPONSIBILITY All analysts are responsible to follow the instruction. 4. PROCEDURE 4.1 Instrument Information Name HPLC Identification No. Model (Pump) L-2100/2130 Model (UV-VIS Detector) L-2420 Range wave length 190-900 nm Operating Temp. Range 15 ºC to 25 ºC 4.2 Method of Operation Connect the instrument to power supply. Switch on...