Testing Methods

Feb82023 by KBS.No Comments

Propylene Glycol (PG) Testing Procedure

Raw Material, Quality Control, SOPs, Testing Methods

Propylene glycol (PG) is commonly tested using gas chromatography (GC) or high-performance liquid chromatography (HPLC). Propylene Glycol (PG) Testing Procedure and methods use separation techniques to isolate and quantify the PG from a sample, which is then measured using a detector. The choice of method depends on the specific requirements of the test, such as the sample size, level of precision, and required analysis time. Other methods, such as infrared spectroscopy (IR), can also be used but may not be as accurate as GC or HPLC. It's recommended to consult with a specialist or refer to industry-specific standards for the best testing method for a particular application. A step-by-step procedure for testing propylene glycol (PG) using gas chromatography (GC) is as follows: Samp...

Feb82023 by KBS.No Comments

SOP for Povidone (PVP) Raw Material Powder Testing

Raw Material, General Topics, Quality Control, SOPs, Testing Methods

Povidone (PVP) is a water-soluble polymer commonly used as a binder, dispersant, or viscosity enhancer in pharmaceuticals. SOP for Povidone (PVP) Raw Material Powder Testing of PVP RM powder typically involves verifying its physical characteristics (e.g. particle size, color, odor) and evaluating its chemical properties (e.g. assay, impurities, dissolution). These tests help to ensure the quality and consistency of the PVP RM powder, and can also help to identify any potential contaminants that might affect the product's safety or efficacy. The specific tests performed will depend on the intended use of the PVP RM powder and may vary based on the manufacturer and regulatory requirements. A Standard Operating Procedure (SOP) is a written document that outlines the steps involved in a labora...

Feb82023 by KBS.No Comments

Water Sampling for Chemical and Microbial Testing

Quality Control, SOPs, Testing Methods

Water sampling for chemical and microbial testing is a crucial process in ensuring the quality and safety of RO and distilled water. Water Sampling for Chemical and Microbial Testing involves collecting a representative portion of water from a source and analyzing it for various chemical and microbial contaminants. For chemical testing, water samples are analyzed for a range of contaminants, including heavy metals, pesticides, and organic pollutants. The methods used for chemical analysis vary but may include spectrophotometry, chromatography, and mass spectrometry. For microbial testing, water samples are analyzed for the presence of pathogenic microorganisms, such as bacteria, viruses, and parasites. Microbial analysis may involve culturing the water sample in a laboratory or using...

Feb82023 by KBS.No Comments

SOP for Monitoring of Raw Water and Potable Water Quality

Testing Methods, Quality Control, SOPs

Raw water refers to water in its natural state, as it exists in a river, lake, or aquifer, SOP for Monitoring of Raw Water and Potable Water Quality without any treatment or purification. Potable water, on the other hand, is water that is safe for human consumption and meets health and quality standards set by regulatory agencies. Potable water typically undergoes treatment processes, such as filtration, disinfection, and removal of impurities, It is important to note that drinking raw water carries health risks, as it may contain pathogens, contaminants, and other harmful substances that can cause illness or disease. Potable water, on the other hand, is treated and tested to reduce these risks and provide a safe source of drinking water OBJECTIVE To lay down a procedure for monitoring o...

Feb82023 by KBS.No Comments

How to Test for Titanium Dioxide

Raw Material, General Topics, Quality Control, SOPs, Testing Methods

Titanium dioxide How to Test for Titanium Dioxide (TiO2) is a white, odorless, and tasteless powder that is widely used as a pigment in various products, including pharmaceutical tablets, sunscreen, food, and cosmetics. It is also used as a whitening and brightening agent, as well as an opacifying agent. Titanium dioxide has good durability and is resistant to discoloration and weathering, which makes it suitable for use in a wide range of applications. Some studies have suggested that Titanium dioxide may be harmful if inhaled or ingested in large quantities, but its safety has been widely evaluated and it is generally considered safe for use in personal care and cosmetic products. Purpose To ensure the quality of incoming raw material of Titanium Dioxide. Scope It is applicable for t...

Feb62023 by KBS.No Comments

How to Test Molnupiravir (Method of Analysis)

Testing Methods, General Topics, Quality Control, Raw Material, SOPs

The testing of Molnupiravir raw material can be done through various methods, How to Test Molnupiravir (Method of Analysis) including High-Performance Liquid Chromatography (HPLC): This method is used to determine the purity and potency of the raw material, Nuclear Magnetic Resonance (NMR) Spectroscopy: This method is used to identify the structure of the raw material, Infrared Spectroscopy (IR): This method is used to identify functional groups in the raw material, Mass Spectrometry (MS): This method is used to determine the molecular weight of the raw material, X-Ray Crystallography: This method is used to determine the crystal structure of the raw material. It is important to follow good manufacturing practices (GMP) and standard operating procedures (SOPs) during the testing process...

Feb62023 by KBS.No Comments

How to Test Tapentadol Hydrochloride

Testing Methods, Quality Control, Raw Material, SOPs

Tapentadol, a centrally acting opioid analgesic, is used in the treatment of moderate to severe acute and chronic pain, as well as the management of neuropathic pain associated with diabetic peripheral neuropathy in adults (extended release formulation only). How to Test Tapentadol Hydrochloride Tapentadol functions as an opiate agonist by binding to mu-opioid receptors and inhibiting norepinephrine reuptake. Approximately 97% of the parent drug is metabolised. The main route of tapentadol metabolism is conjugation with glucuronic acid to produce glucuronides. Tapentadol and its metabolites (N-desmethyltapentadol and hydroxyl-tapentadol) are excreted almost entirely through the kidneys, with the conjugated form accounting for approximately 70% of the drug excreted in urine. Tapentadol meta...

Feb62023 by KBS.No Comments

What is Raw Water Testing (Method of Analysis)

Testing Methods, General Topics, Quality Control, SOPs

Reverse osmosis water, or What is Raw Water Testing (Method of Analysis), is water that has undergone a reverse osmosis filtration process. In order to produce pure water, this process includes putting water through a semi-permeable membrane that filters out dissolved salts, minerals, and other contaminants. When water purity is crucial, reverse osmosis is frequently distilled for industrial and commercial applications as well as domestic water filtration systems. Distilled water is water that has through the distillation process, which entails heating water to the boiling point and then condensing the steam back into a liquid form, producing clean water with contaminants and minerals eliminated. This makes distilled water perfect for use in machinery, batteries, and scientific experime...

Jan312023 by KBS.No Comments

Sampling and Testing of Packing Materials

Testing Methods, Production, Quality Assurance, Quality Control

The Sampling and Testing of Packing Materials should take account of at least the following: the quantity received, the quality required, the nature of the material (e.g. primary packaging materials and/or printed packaging materials), the production methods, and what is known of the Quality Assurance system of the Sampling and Testing of Packing Materials manufacturer based on audits. The number of samples taken should be determined statistically and specified in a sampling plan. Sampling and Testing of Packing Materials is an important operation in which only a small fraction of a batch is taken. Valid conclusions on the whole cannot be based on tests which have been carried out on non representative samples. Correct sampling is thus an essential part of a system of Quality Assurance....

Jan302023 by KBS.No Comments

Sampling and Testing of In process and Finished Products

Quality Control, Product, Production, SOPs, Testing Methods

The objective of in Sampling and Testing of In process and Finished Products is to verify that all applicable specifications and requirements pertaining to product are fulfilled and to prepare corresponding documents so as to check that testing parameters met the intended specifications and requirements through out the production run. Purpose:- This SOP is established to provide the guidelines for the sampling & testing of in process and finished products so as to get the representative sample of the whole batch for analysis. Sampling and Testing of In process and Finished Products Additionally, the objective of the in process & final testing is to provide objective evidence of product conformance to specification and continued effectiveness of the quality management system. ...