KBS. - Pharma Egg - Page 24 of 25

Jan82022 by KBS.No Comments

Amlodipine Besylate Raw Material (API) SAP

Amlodipine Besylate Raw Material (API) is the best-prescribed Raw Material (API) for cardiovascular ailment main hazard element for high blood pressure. First mentioned low fee ultraviolet-seen method for the dedication and quantitation of medicine in prescription drugs and organic fluids. Chromatographic strategies have an utility with appreciate to hint evaluation. Different sorts of chromatography together with excessive-overall performance liquid chromatography, excessive overall performance skinny layer chromatography have maximum common packages withinside the subject of pharmaceutical in addition to biomedical analyses. Amlodipine Besylate Raw Material (API) Chromatography mixed with mass spectrophotometry has the capacity to acquire molecular ion. Amlodipine Besylate Raw Mater...

Jan42022 by KBS.No Comments

Calibration SOPs for UV Spectrophotometer

SOPs

Calibration is one of the most frequently used techniques in pharmaceutical analysis. This involves measuring the amount of ultraviolet radiation or seen absorbed by a substance in the solution. The calibration instrument measures the ratio, or function ratio, from the intensity of two light beams in Qualitative UV analysis, organic compounds can be identified using spectrophotometers, if there are recorded data available, and quantitative spectrophotometric analysis is used to ensure the quantity of molecular species that absorb radiation. Calibration of spectrophotometric techniques are simple, fast, quite specific and applies to small quantities of compounds. Fundamental law that regulates calibration spectrophotometrically analysis PURPOSE: To describe the Calibration procedure for...

Jan42022 by KBS.No Comments

Operational SOPs for UV/VIS Spectrophotometer

SOPs

UV/VIS Spectrophotometer Operational SOPs method is used to measure the pharmaceutical and non-pharmaceutical compounds that have detectable peaks in the UV-Vis region PURPOSE: To describes the operating procedure for operation of UV/VIS Spectrophotometer. SCOPE: This SOP gives detailed outline for the operation of UV/VIS Spectrophotometer and will cover operating procedure of equipment. RESPONSIBILITY: QC Analyst is responsible for operation of equipment and preparing standard operating procedure. It is the responsibility of QC Manager to assist and ensure Operating Procedure’s as per SOP and to make certain that this SOP is followed in its entirety, reviewed regularly and revised as necessary. REFERENCE: In-House Specifications MATE...

Jan42022 by KBS.No Comments

HPLC Waters Pda With Quartnary Pump – SOPs

SOPs

This SOP HPLC WATERS PDA WITH QUARTNARY PUMP most important who gives a detailed outline for the operation of HPLC 1 Waters PDA With Quartnary Pump and will cover the operating procedure, calibration and cleaning of equipment. PURPOSE: To describes the operating procedure for operation of HPLC 1 Waters PDA With Quartnary Pump. SCOPE: This SOP gives detailed outline for the operation of HPLC 1 Waters PDA With Quartnary Pump and will cover operating procedure, calibration and cleaning of equipment. RESPONSIBILITY: QC Analyst is responsible for the operation of equipment and preparing standard operating procedures. It is the responsibility of QC Manager to assist and ensure Operating Procedure as per SOP and to make certain that this SOP is ...

Jan32022 by KBS.1 Comment

Cleaning SOPs for UV Spectrophotometer

SOPs, Quality Control

In this article detail is given of Cleaning SOPs for UV Spectrophotometer, how to clean UV Spectrophotometer in Quality control Laboratory of Pharmaceuticals. OBJECTIVE To lay down the procedure for cleaning of UV/VIS Spectrophotometer. SCOPE: This shall be applicable to the UV/VIS Spectrophotometer installed in Quality Control instrument Laboratory. RESPONSIBILITY: Technical Assistant/ Helper. C Analyst. ACCOUNTABILITY: Manager-Quality Control. MATERIAL AND EQUIPMENT: UV/VIS Spectrophotometer. Clean dry cloth. Tissue paper. Dilute soap solution. Purified water. PROCEDURE: Ensure that the power supply to the instrument is switched OFF before cleaning. After completion of the testing, remove cuve...

Jan32022 by KBS.No Comments

Washing Of HPLC Column SOP

SOPs

Here is the WASHING OF HPLC COLUMN, it is very important in the laboratory, if not done can correctly affect the health of your column. Cleaning your HPLC column may be simple, but it is very important for efficiency, lifetime, and productivity instruments. The ineffective HPLC column can affect your analysis, resulting in inaccurate results, which means more time spent on the same project. The following SOP focuses only on how to clean your HPLC column through reverse flushing. It may be time to water your HPLC column when you see high back pressure, low efficiency, split peak, or the most common problem, the particulate buildup in the head of the column. Now we move to Washing Of HPLC Column SOP Objective: This method is applicable for washing of HPLC column. Sco...

Jan32022 by KBS.1 Comment

Operational SOPs for HPLC (High Performance Liquid Chromatography)

SOPs

In this post, we will study Operational SOPs for HPLC (High Performance Liquid Chromatography). All the related outline, scope, responsiblity and procedure you will study here. 1. PURPOSE To outline work instruction for “HPLC” in Quality Control Department. 2. SCOPE To separation of different material in solution in Quality Control Department. 3. RESPONSIBILITY All analysts are responsible to follow the instruction. 4. PROCEDURE 4.1 Instrument Information Name HPLC Identification No. Model (Pump) L-2100/2130 Model (UV-VIS Detector) L-2420 Range wave length 190-900 nm Operating Temp. Range 15 ºC to 25 ºC 4.2 Method of Operation Connect the instrument to power supply. Switch on...

Jan32022 by KBS.No Comments

Melting Point Apparatus use in Pharmaceuticals

Quality Control

Pharmaceutical Melting Point Apparatus equipment is designed to quickly measure the Melting range and point of certain substances. Some samples can be tested simultaneously and safely in the analyzer of the Bench-Top Melting point. Purchasing considerations for Pharmaceutical Laboratory Melting Point Analyzer includes the temperature range of instruments, user interfaces, and test heating times. Melting point apparatus is a laboratory device used to determine the melting point of an element with precision and large accuracy. The temperature in which the state of a substance changes from solid to the liquid is said to be the melting point. Melting a substance is generally obtained by heating it. This is one of the most important and basic parameters to know about the nature of a substanc...

Jan32022 by KBS.No Comments

Disintegration Apparatus use in Pharmaceuticals Industry

Quality Control

Disintegration Apparatus testers are used to test how drugs in the form of pellets will be destroyed in solution. Like the testers of dissolution, they allow researchers and medical practitioners to analyze in vitro details of powder compounds for quality control purposes. Standard disintegration tester A.S. Pharmacopeia uses three baskets with round mesh (or mesh sample tube), which slowly moved up and down in the water bath at 37 ° C. The tablet is placed in the basket of the disintegration tester and the time taken for them destroyed; Or, disintegration testers can be used for pass / failed to see if the tablet will dissolve completely, if at all. Simple tools such as disintegration testers must be assessed with their relative compactness, the quality and accuracy of their temperature c...

Jan32022 by KBS.No Comments

ph Meter use in Pharmaceuticals

Quality Control

The pH is a measure of alkalinity& an aqueous solution’s acidity. This is dependent on the comparative number of hydrogen ions (H+) or hydroxyl ions (OH-) in the solution. Higher relative number of hydrogen ions; conversely, alkaline solutions have a higher relative number of OH- ions in acidic solution. In water, the absorption of H+ and OH‑ may vary over 15 orders of magnitude. The Henderson–Hasselbalch equation allows pH to be derived from the quantity of H+ using pKa, the negative log of the acid dissociation constant, in biological and chemical systems. Most of the Pharmaceuticalsas part of their process measure pH to assure product quality. A pH meter is a scientific instrument that measures the hydrogen ion activity in water-based solutions, indicating its acidity or alkalinit...